Best time to take metformin 500 mg once a day

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    • When Is The Best Time To Take Metformin?

    Apr 27, 2019

    Kathy asked

    Can you tell me the best time to take metformin?

    At a glance

    • Metformin should always be taken with food.

      Immediate-release products should be taken in divided doses with meals while extended-release products should be taken with the evening meal.

    Answer

    When to take metformin depends on which product you are taking as there are several different ones.

    They are:

    • Immediate-release tablets
    • Extended-release tablets (which includes Glucophage XR, Glumetza and Fortamet)
    • Solution

    In the next sections, I discuss when it is recommended to take metformin based on which product you are taking.

    Immediate-Release

    Immediate-release metformin tablets should be taken with meals.

    Per the prescribing information for metformin:[1]

    GLUCOPHAGE [immediate-release metformin] should be given in divided doses with meals.Glucophage Prescribing Information

    Extended-Release

    There are three different extended-release metformin products:

    • Glucophage XR
    • Glumetza
    • Fortamet

    All 3 products utilize diffe

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